Fig. 3.

Left: General dependence of transcriptional activity on the concentration of transcription factors for enhancers and super-enhancers. Right: Dependence of enhancer and super-enhancer activity on valence (i.e., the number of available intermolecular interactions according to the phase separation model). The regular enhancer is modeled by a system consisting of 10 molecules, whereas the super-enhancer is modeled by 50 molecules. Adapted from [14]