Table 3. Analysis of high-depth regions under SmartMap analysis.

	Number of genomic windows with:				Percent of genomic windows with:
Dataset	>60 rds.	>70 rds.	>80 rds.	>90 rds.	>60 rds.	>70 rds.	>80 rds.	>90 rds.
Gold Std.	34,468	463	1	0	0.22	0.0030	6.5 x 10−6	0
Iteration 0	26,969	571	85	36	0.17	0.0037	5.5 x 10−4	2.3 x 10−4
Iteration 1	44,185	10,193	6,337	4,296	0.29	0.066	0.041	0.028
Uniread	24,344	321	1	0	0.16	0.0021	6.5 x 10−6	0

Number of genomic windows refers to the number of 200bp genomic windows for each dataset with an average depth or average weight greater than that indicated in each column. Percent of genomic windows refers to the number of genomic windows as a percentage of the total number of 200bp genomic windows in hg38 (15,498,848). The median read depth was 10.5 and the mean read depth was 16.1 in the Gold Standard dataset.