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. 2021 Apr 19;19(4):e3001201. doi: 10.1371/journal.pbio.3001201

Fig 6. Weight loss, viremia, and ZIKV antibody responses postprimary ZIKV infection.

Fig 6

(A) Timeline of experiment. (B) Weight loss of IFNAR−/− mice postinfection (n = 5 mice per group). (C) Viremia postinfection of mice infected with WT ZIKV or CpG_max or UpA_max ZIKV. (D) 50% End-point of total IgG ELISA titers 4 weeks postvaccination with indicated ZIKV mutants. Significant changes from WT are calculated by a one-way ANOVA with Dunett multiple comparisons test and indicated with asterisks (p < 0.05). Numerical values for panels B–D are available in S1 Data. IgG, immunoglobulin G; SCR, scrambled control virus; WT, wild-type; ZIKV, Zika virus.