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. 2019 Aug 22;26(4):394–404. doi: 10.5603/CJ.a2018.0049

Figure 4.

Figure 4

Deficient AMIGO2 decreased infarct size, activated the PDK-1, Pten, Akt, Bcl-2/Bax and VEGF signalling pathways in cardiomyocytes (CMs) and endothelial cells (ECs) at the levels of the mRNAs and protein; A. Representative Masson’s trichrome staining of the heart to show the infarct zone 28 days after myocardial infarction; B. Quantification of infarct zone in heart tissue; &p < 0.01 vs. the Wild-type (WT) group; C, D. Quantitative analysis of mRNA expression of PDK-1, Pten, Akt, Bcl-2/Bax, caspase-3 and VEGF; #p < 0.01 vs. the WT group; E, F. Quantitation of PDK-1, Pten, Akt, Bcl-2/Bax, caspase-3 and VEGF expression in CMs and ECs, n = 3; #p < 0.01 vs. the WT group; G. H. Western blotting identification for altered expression of NF-κB/p56 Akt, Bcl-2/Bax, caspase-3 and VEGF.