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The segments of the original recordings obtained from individual rats in each experimental group show the responses of the renal sympathetic nerve activity (RSNA). Mean changes in RSNA after the microinjection of anti-HMGB1 polyclonal antibody into the paraventricular nucleus vs. the sham group; p < 0.001; MI+Anti-HMGB1 polyclonal antibody treatment group vs. the MI group; p < 0.001.
