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Values in individual participants for Glutamate (Glucorr) and Glx (Glxcorr, glutamate plus glutamine) in the anterior cingulate cortex (ACC) and right caudate before and 12 weeks after switching to clozapine (left). The right column presents data as percentage reduction. In the caudate, Glucorr was significantly reduced after 12 weeks of clozapine treatment (P = .01).
