Table 1. Percentage amino acid identity of canine and feline coronavirus spike and nucleocapsid proteins with SARS-CoV-2 proteins, the Netherlands*.
| Genus | Virus | SARS-CoV-2 |
|||
|---|---|---|---|---|---|
| N | S | S1 | RBD | ||
| Betacoronavirus | CRCoV | 32.4 | 28.5 | 20.0 | 15.6 |
| Alphacoronavirus | FCoV type I | 29.0 | 24.0 | 16.8 | 7.7 |
| Alphacoronavirus | FcoV type II | 27.8 | 25.3 | 17.7 | 8.9 |
| Alphacoronavirus | CCoV | 28.0 | 25.1 | 16.9 | 8.9 |
*SARS-CoV-2, CRCoV, FCoV type I, FCoV type II, CCoV (GB: NC_045512.2, JX860640.1, FJ938060.1, AY994055.1, KC175341.1). Amino acid sequences were aligned by using Clustal W (https://www.ebi.ac.uk/Tools/msa/clustalo), and pairwise identities were calculated by using the needle method in the EMBOSS pairwise alignment algorithms program (https://www.ebi.ac.uk/Tools/psa/emboss_needle). CCoV, canine coronavirus; CRCoV, canine respiratory coronavirus; FCoV, feline coronavirus, N, nucleocapsid protein; RBD, receptor-binding domain; S, spike protein; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; S1, spike protein subunit 1.