Table. Amino acid changes within the spike protein sequence of the HMN.19B variant in France compared with the reference sequence of the international GISAID database (GenBank accession no. NC_045512.2), in comparison with other recently identified SARS-CoV-2 variants*.
| Spike protein sequence | ||||
|---|---|---|---|---|
| HMN.19B (Henri Mondor variant) | 20I/501Y.V1 (UK variant) | 20H/501Y.V2 (South African variant) | P1 20J/501Y.V3 (Brazilian variant) | CAL.20C (Californian variant) |
| S13I | ||||
| L18F | L18F | L18F | ||
| T20N | ||||
| P26S | ||||
| Del69/70 | ||||
| D80A | ||||
| D138Y | ||||
| Del144 | ||||
| W152C | ||||
| R190S | ||||
| D215G | ||||
| Del 242–244 | ||||
| R246I | ||||
| K417N | K417T | |||
| L452R | L452R | |||
| E484K | E484K | |||
| N501Y | N501Y | N501Y | N501Y | |
| A570D | ||||
| A653V | ||||
| H655Y | H655Y | |||
| Q677H† | ||||
| P681H | ||||
| A701V | ||||
| T716I | ||||
| D796Y | ||||
| S982A | ||||
| T1027I | ||||
| D1118H | ||||
| G1219V | ||||
*Bold type indicates amino acid changes observed in >1 of the recent variants. †Inconstantly detected, recently found in the genome of the “Midwest” variant (Q677H variant) observed in Ohio (USA) in December 2020 and January 2021.