. 2021 Apr 30;92:104888. doi: 10.1016/j.meegid.2021.104888

Table 2.

Frequencies of disease associated variants of ACE2 in world populations.

Variant ID	Reference allele	Variant allele	Frequency of variant allele
				AFR							AMR				EAS					EUR					SAS
			ALL^a	YRI	LWK	GWD	MSL	ESN	ASW	ACB	MXL	PUR	CLM	PEL	CHB	JPT	CHS	CDX	KHV	CEU	TSI	FIN	GBR	IBS	GIH	PJL	BEB	STU	ITU
rs4830542	T	C	0.32	*0.63*	*0.48*	*0.59*	*0.56*	*0.55*	*0.42*	*0.52*	0.21	*0.36*	*0.37*	0.15	0.04	0.03	0.03	0.06	0.03	*0.38*	*0.40*	*0.34*	*0.28*	*0.35*	*0.31*	*0.33*	0.22	*0.26*	*0.29*
rs2074192	C	T	0.36	*0.3*	*0.42*	*0.29*	*0.36*	*0.32*	*0.41*	*0.35*	*0.42*	*0.34*	*0.34*	*0.53*	*0.46*	*0.43*	*0.41*	*0.37*	*0.47*	*0.35*	*0.42*	*0.46*	*0.5*	*0.41*	0.24	*0.28*	0.25	0.18	0.18
rs233575	A	G	0.14	0.00	0.02	0.01	0.00	0.00	0.07	0.01	0.18	0.21	*0.32*	0.12	0.01	0.00	0.00	0.01	0.00	*0.36*	*0.4*	*0.29*	*0.27*	*0.34*	0.19	*0.26*	0.15	0.14	0.17
rs1514280	G	A	0.20	0.20	0.15	*0.30*	0.23	0.25	0.18	0.14	0.20	*0.29*	*0.34*	0.12	0.01	0.00	0.00	0.01	0.00	*0.38*	*0.39*	*0.33*	*0.27*	*0.35*	0.22	*0.26*	0.17	0.15	0.18
rs4240157	T	C	0.32	*0.63*	*0.48*	*0.59*	*0.55*	*0.56*	*0.42*	*0.52*	0.21	*0.36*	*0.37*	0.15	0.04	0.03	0.03	0.06	0.03	*0.38*	*0.4*	*0.36*	*0.29*	*0.35*	*0.31*	*0.33*	0.22	*0.26*	*0.29*
rs879922	G	C	0.32	*0.63*	*0.49*	*0.6*	*0.55*	*0.56*	*0.42*	*0.52*	0.21	*0.36*	*0.37*	0.14	0.04	0.03	0.03	0.06	0.03	*0.39*	*0.4*	*0.34*	*0.28*	*0.36*	*0.32*	*0.33*	0.22	*0.27*	*0.29*
rs4646156	T	A	0.20	0.22	0.24	0.19	0.17	0.17	0.18	0.20	0.17	*0.36*	*0.30*	0.12	0.01	0.00	0.00	0.02	0.01	*0.40*	*0.38*	*0.33*	*0.29*	*0.34*	0.23	*0.28*	0.16	0.17	0.17
rs4646155	C	T	0.06	0.19	0.09	0.16	0.11	0.17	0.10	0.10	0.01	0.04	0.01	0.01	0.04	0.03	0.03	0.05	0.03	0.00	0.01	0.00	0.00	0.00	0.09	0.06	0.05	0.11	0.11
rs4646188	A	G	0.04	0.00	0.00	0.00	0.00	0.00	0.01	0.01	0.03	0.05	0.03	0.02	0.00	0.00	0.00	0.00	0.00	0.09	0.10	0.13	0.21	0.14	0.07	0.09	0.05	0.04	0.06
rs4646142	G	C	0.36	0.19	0.17	*0.31*	0.24	*0.28*	*0.26*	0.24	*0.36*	*0.27*	*0.37*	*0.36*	*0.51*	*0.55*	*0.56*	*0.55*	*0.53*	*0.26*	0.19	*0.26*	0.24	0.25	*0.4*	*0.4*	*0.55*	*0.53*	*0.52*
rs2048683	G	T	0.20	0.21	0.23	0.19	0.17	0.17	0.17	0.20	0.17	*0.36*	*0.3*	0.12	0.01	0.00	0.00	0.02	0.01	*0.41*	*0.39*	*0.34*	*0.29*	*0.34*	0.23	*0.26*	0.16	0.17	0.16
rs2285666	C	T	0.35	0.17	0.16	*0.3*	0.21	0.19	0.24	0.21	*0.36*	*0.27*	*0.37*	*0.36*	*0.51*	*0.55*	*0.56*	*0.55*	*0.52*	*0.26*	0.19	*0.26*	0.22	0.25	*0.40*	*0.40*	*0.55*	*0.53*	*0.52*
rs6632677	G	C	0.02	0.00	0.00	0.00	0.00	0.00	0.01	0.00	0.04	0.01	0.03	0.06	0.09	0.10	0.08	0.04	0.03	0.01	0.00	0.00	0.00	0.00	0.00	0.01	0.02	0.01	0.00
rs2106809	A	G	0.32	0.07	0.08	0.09	0.10	0.04	0.12	0.12	*0.36*	*0.26*	*0.34*	*0.36*	*0.52*	*0.51*	*0.56*	*0.51*	*0.51*	*0.26*	0.20	0.24	*0.26*	*0.28*	*0.39*	*0.40*	*0.53*	*0.56*	*0.54*
rs1978124	C	T	0.21	0.13	0.10	0.08	0.07	0.11	0.16	0.06	0.21	*0.40*	*0.38*	0.12	0.01	0.00	0.00	0.02	0.01	*0.52*	*0.52*	*0.48*	*0.41*	*0.43*	*0.27*	*0.28*	0.18	0.19	0.17

All populations (ALL); African super-population (AFR)- ((Yoruba in Ibadan, Nigeria (YRI); Luhya in Webuye, Kenya (LWK); Gambian in Western Divisions in the Gambia (GWD); Mende in Sierra Leone (MSL); Esan in Nigeria (ESN); Americans of African Ancestry in SW USA (ASW); African Caribbeans in Barbados (ACB)); Ad Mixed American (AMR)- ((Mexican Ancestry from Los Angeles USA (MXL); Puerto Ricans from Puerto Rico (PUR); Colombians from Medellin, Colombia (CLM); Peruvians from Lima, Peru (PEL)); East Asian (EAS)- ((Han Chinese in Beijing, China (CHB); Japanese in Tokyo, Japan (JPT); Southern Han Chinese (CHS); Chinese Dai in Xishuangbanna, China (CDX); Kinh in Ho Chi Minh City, Vietnam (KHV)); European (EUR)- ((Utah Residents (CEPH) with Northern and Western European Ancestry (CEU); Toscani in Italia (TSI); Finnish in Finland (FIN); British in England and Scotland (GBR); Iberian Population in Spain (IBS)); South Asian (SAS)- ((Gujarati Indian from Houston, Texas (GIH); Punjabi from Lahore, Pakistan (PJL); Bengali from Bangladesh (BEB); Sri Lankan Tamil from the UK (STU); Indian Telugu from the UK (ITU)).