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. 2021 Apr 6;40(17):3101–3117. doi: 10.1038/s41388-021-01768-8

Fig. 4. PTPRD promotes radiation-induced autophagy in NPC cells.

Fig. 4

A–D Expression of LC3 and P62 was detected in PTPRD-overexpressing or control cells after radiation exposure (0–10 Gy) and culture for 24 h subsequently. These data are representative of three independent experiments. E Treatment with Baf-A1 caused significant increases in LC3-II accumulation in PTPRD-overexpressing cells after radiation exposure (6 Gy) and culture for 24 h subsequently. These data are representative of three independent experiments. F, G Immunofluorescence staining images and statistical analysis of LC3 in PTPRD-overexpressing HONE1 and HK1-EBV cells after radiation exposure or Baf-A1 treatment and culture for 24 h subsequently. These data are representative of three independent experiments. Mean ± SD (n = 3); Student’s t tests; ***P < 0.001.