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. 2021 Mar 18;46(6):1359–1371. doi: 10.1007/s11064-021-03270-9

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Fig. 2 — UCP2 deficiency enhanced NLRP3 inflammasome activation after cerebral I/R damage in hyperglycemic mice. a The expression of NLRP3, cleaved caspase 1, caspase 1, ASC, TXNIP, and IL-1β in the different groups of UCP2-/- and WT mice. b–g Semiquantitative analysis of NLRP3, cleaved caspase 1, caspase 1, ASC, TXNIP, and IL-1β protein expression. h, i The level of IL-1β and IL-18 in serum. ^@p < 0.05 vs. the sham group; ^#p < 0.05 vs. the WT group; ^*p < 0.05 vs. the NG group (n = 6 in each group)