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. 2021 Mar 18;46(6):1359–1371. doi: 10.1007/s11064-021-03270-9

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© The Author(s) 2021

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Fig. 3 — UCP2 deficiency promotes NLRP3 inflammasome activation in neurons under hyperglycemia-exacerbated cerebral I/R conditions. a Representative images showing double immunofluorescence staining for NLRP3 (red) and NeuN (green) in the cortical penumbra area. b Representative images of double immunofluorescence staining for cleaved caspase 1 (red) and NeuN (green) in the cortical penumbra area. c The percentage of NLRP3-positive cells in the cortical penumbra area. d The percentage of cleaved caspase 1-positive cells (%) in the cortical penumbra area. ^@p < 0.05 vs. the sham group; ^#p < 0.05 vs. the WT group; *p < 0.05 vs. the NG group (n = 6 in each group)