Table 2.

Sensitivity and specificity for severe adverse events, stratified by age group in the HUS and STEC cohorts.

Age group (years)	Sensitivity (%) (95% CI)	Specificity (%) (95% CI)	AUC (95% CI)
HUS Cohort
Overall	89.4 (81.3, 94.8)	44.3 (31.5, 57.6)	0.71 (0.63, 0.79)
0 to <5	86.8 (74.7, 94.5)	56.8 (39.5, 72.9)	0.77 (0.68, 0.87)
≥5 to <10	93.9 (79.8, 99.3)	35.3 (14.2, 61.7)	0.71 (0.56, 0.86)
≥10	87.5 (47.3, 99.7)	0.0 (0.0, 41.0)	0.57 (0.25, 0.89)
STEC Cohort
Overall	89.2 (79.8, 95.2)	19.7 (16.5, 23.3)	0.58 (0.51, 0.65)
0 to <5	87.2 (72.6, 95.7)	40.7 (34.1, 47.6)	0.75 (0.66, 0.84)
≥5 to <10	92.9 (76.5, 99.1)	12.2 (7.4, 18.5)	65.2 (52.8, 77.6)
≥10	85.7 (42.1, 99.6)	1.6 (0.3, 4.6)	0.644 (0.41, 0.87)

Abbreviations: AUC, area under the curve; CI, confidence interval; HUS, hemolytic uremic syndrome; STEC, Shiga toxin-producing Escherichia coli