Table 1.
Patient demographics, tumor characteristics and treatment options of 4975 elderly with glioblastoma.
| Characteristics | All | Biopsy (%) | GTR (%) | STR (%) | P value |
|---|---|---|---|---|---|
| Population size | 4975 | 1191 (23.9) | 2558 (51.4) | 1226 (24.5) | |
| Age group | < 0.001† | ||||
| < 75 | 3285 | 741 (22.6) | 1753 (53.4) | 791 (24.0) | |
| ≥ 75 | 1690 | 450 (26.6) | 805 (47.6) | 435 (25.8) | |
| Sex | 0.143 | ||||
| Female | 2202 | 542 (24.2) | 1171 (52.5) | 523 (23.3) | |
| Male | 2733 | 649 (23.8) | 1381 (50.5) | 703 (25.7) | |
| Race | 0.003† | ||||
| Black | 207 | 65 (31.4) | 103 (49.8) | 39 (18.8) | |
| Other | 231 | 53 (22.9) | 103 (44.6) | 75 (32.5) | |
| White | 4537 | 1073 (23.7) | 2352 (51.8) | 1112 (24.5) | |
| Marital status | 0.007† | ||||
| Divorced/separated | 410 | 108 (26.3) | 204 (49.8) | 98 (23.9) | |
| Married/partner | 3343 | 745 (22.3) | 1754 (52.5) | 844 (25.2) | |
| Single | 414 | 117 (28.3) | 192 (46.4) | 105 (25.4) | |
| Widowed | 808 | 221 (27.4) | 408 (50.5) | 179 (22.1) | |
| Insurance | 0.047† | ||||
| Privately insured | 4600 | 1096 (23.8) | 2370 (51.5) | 1134 (24.7) | |
| Medicaid | 348 | 85 (24.4) | 182 (52.3) | 81 (23.3) | |
| Uninsured | 27 | 10 (37.0) | 6 (22.2) | 11 (40.7) | |
| Primary site | < 0.001† | ||||
| Temporal | 1595 | 321 (20.1) | 883 (55.4) | 391 (24.5) | |
| Cerebrum | 70 | 47 (67.1) | 8 (11.4) | 15 (21.5) | |
| Frontal | 1406 | 329 (23.4) | 728 (51.8) | 349 (24.8) | |
| Parietal | 899 | 232 (25.8) | 457 (50.8) | 210 (23.4) | |
| Occipital | 273 | 57 (20.9) | 156 (57.1) | 60 (22.0) | |
| Ventricle | 10 | 4 (40.0) | 4 (40.0) | 2 (20.0) | |
| Cerebellum | 29 | 8 (27.6) | 16 (55.2) | 5 (17.2) | |
| Brainstem | 1 | 1 (100) | 0 (0.0) | 0 (0.0) | |
| Overlapping | 692 | 192 (27.8) | 306 (44.2) | 194 (28.0) | |
| Size | < 0.001† | ||||
| > 5.4 cm | 1337 | 300 (21.8) | 6661 (48.4) | 411 (29.8) | |
| ≤ 5.4 cm | 3598 | 891 (24.8) | 1892 (52.6) | 815 (22.7) | |
| Metastasis | 0.014† | ||||
| No | 4928 | 1178 (23.9) | 2543 (51.6) | 1207 (24.5) | |
| Yes | 47 | 13 (27.7) | 15 (31.9) | 19 (40.3) | |
| Adjuvant therapy | < 0.001† | ||||
| No/unknown | 861 | 241 (28.0) | 430 (49.9) | 190 (22.1) | |
| Radiotherapy | 530 | 153 (28.9) | 252 (47.5) | 125 (23.6) | |
| Chemotherapy | 142 | 36 (25.4) | 79 (55.6) | 27 (19.0) | |
| ChemoRT | 3442 | 761 (22.1) | 1797 (52.1) | 884 (25.7) |
GTR gross total resection, STR subtotal resection.
†P < 0.05, statistically significant.