Table 2.

Frequency of Treatment Related Adverse Events and Laboratory Abnormalities.

Event	Any Grade	Grade ≥ 3
Any event – no. (%)	41 (100)	14 (34)
Any serious event – no. (%)	1 (2)	1 (2)
Most common events – no. (%)
Fatigue	24 (59)	1 (2)
Nausea	21 (51)	0
Anorexia	10 (24)	0
Diarrhea	9 (22)	1 (2)
Vomiting	9 (22)	0
Peripheral sensory neuropathy	6 (15)	1 (2)
Laboratory Abnormalities – no. (%)
Anemia	19 (46)	2 (5)
Neutrophil count decrease	16 (39)	8 (20)
Lymphocyte count decrease	12 (29)	4 (10)
Platelet count decreased	13 (32)	2 (5)
White blood cell count decreased	10 (24)	3 (7)
Alkaline phosphatase increased	6 (15)	0

AE with > 10% incidence