Fig. 5.

a Total and phosphorylated forms of JAK2 in HDFs were was measured by western blot after transfection with miR-210-5p mimic or inhibitor. b Graphical representation of the miR-210-5p binding motif at the 3′-UTR of STAT5A. c The luciferase activity displayed by the luciferase reporter constructs which contained either the wild type (WT) or mutation (MU) of STAT5A 3′-UTR after miR-210-5p mimic transfection. d, e) The expression of STAT5A in HDFs was measured by western blot or qPCR after transfection with miR-210-5p mimic or inhibitor. Data are represented as the mean ± SEM. Student's t test was performed to analyze the differences (*P < 0.05; **P < 0.01 in comparison with the indicated group)