Table 5:
Gamma Regression (with log link) parameter estimates and 95% confidence intervals when modeling transplantation status on IL-2 GNB cytokine concentration
Gamma Regression (with log link) parameter estimates and 95% confidence intervals when modeling transplantation status on IL-2 GNB cytokine concentration (N=59) | ||
---|---|---|
Covariates | Estimate (95% CI) | P-value |
Intercept | 4.71 (3.86, 5.56) | <0.0001 |
Transplantation Status | −3.94 (−6.91, −0.97) | 0.009 |
Source of Infection (Reference = GU) | Reference | |
GU | ||
Endovascular Infection | −1.82 (−3.30, −0.33) | 0.02 |
GI | 0.39 (−0.38, 1.16) | 0.32 |
Joint | −2.18 (−4.45, 0.09) | 0.06 |
Respiratory/Lung | 1.00 (−0.42, 2.41) | 0.17 |
Skin/soft tissue | −0.56 (−2.85, 1.73) | 0.63 |
Unknown | 0.22 (−0.87, 1.33) | 0.69 |
Immunosuppressive Regimen (Reference = None) | Reference | |
None | ||
Monotherapy (steroid) | 1.18 (−0.68, 3.05) | 0.21 |
CNI + steroid or CNI + antimetabolite | 2.74 (−0.76, 6.23) | 0.12 |
CNI + mTOR inhibitor + steroid | 1.69 (−1.48, 4.87) | 0.30 |
CNI + antimetabolite + steroid | 2.32 (−0.64, 5.28) | 0.12 |
Duration of Symptoms (48 hours or more) (Reference: < 48 hours) | −0.57 (−1.28, 0.13) | 0.11 |
Septic Shock | −0.82 (−1.69, 0.05) | 0.07 |
GNB, gram-negative bacteremia; CI, confidence interval; GU, genitourinary; GI, gastrointestinal; CNI, calcineurin inhibitor.