Fig. 12.

A 37 y/o female with known Systemic Lupus Erythematosus (SLE), presented with abdominal pain and diarrhea. a Axial T2-W sequence shows focal circumferential mural thickening (thick arrow) of the descending colon. Intense bowel wall diffusion restriction is noted on DWI (b) and ADC (c) sequences (arrowheads). On the post contrast axial T1-W image (d), there is lack of mural enhancement (thin arrow), favoring Lupus-induced ischemic colitis (intermediate stage). Accompanying mild serosal enhancement (dotted arrow) suggests underlying inflammation secondary to vasculitis. e Colonoscopic view of the same segment demonstrated fragile and edematous mucosa with loss of vascularity