TABLE 1.

Bacterial TS genes and their respective functions.

Bacteria	Trx Genes	TrxR Genes	Function	References
Staphylococcus aureus	trxA	trxB	Thioredoxin and thioredoxin reductase genes respond to oxygen and disulfide stress	Uziel et al., 2004
Helicobacter pylori	trxA and trxC	trxR	Required for colonization and survival	Baker et al., 2001
Mycobacterium tuberculosis	trxA, trxB and trxC	trxR	Needed for survival against reactive oxygen and nitrogen species produced by activated macrophages	Trivedi et al., 2012
Bacillus subtilis	TrxA	trxA and trxB	Needed for survival and virulence	Zheng et al., 2019
Escherichia coli	trxA and trxC	trxB	Used to prevent oxidative damage from reactive nitrogen intermediates	St. John et al., 2001; Potamitou et al., 2002