Table 2.
The main components of the basement membrane and their functions.
| Molecules | Secreting cells | Functions | References |
|---|---|---|---|
| Collagen type IV | Mesenchymal, enteroendocrine and epithelial cells | BM stabilization Interaction with transmembrane receptors |
(18) |
| Laminins | Epithelial cells, Mesenchymal cells |
BM assembly Modulation of epithelium homeostasis |
(19–21) |
| Nidogens | Epithelial cells, Mesenchymal cells |
BM stabilization Interaction with ECM components |
(22, 23) |
| Perlecan | Epithelial cells, Mesenchymal cells |
Cell differentiation, proliferation, adhesion and migration | (24–28) |