Table 2.
The “water fed state” operating conditions of TIM-1 digestion system used to digest waffles.
 | |
|---|---|
| Parameters of in vitro digestion | |
| Gastric compartment | |
| pH | 5.7 at T0 to 1.7 at T360 see chart above |
| Volume | 300 mL |
| Secretions | 520 U/ min pepsin, 2 U/ min lipase, and 5 U/ min amylase |
| Time of half emptying | T1/2 = 70 min |
| β coefficient | 2.5 |
| Duodenal compartment | |
| pH | ~ 6.2 |
| Volume | 55 mL |
| Secretions | Bile (20 mg/min for the first 30 min after which 10 mg/ min), pancreatic juice (80 mg/ min) and Sodium bicarbonate solution (as required) |
| Jejunal compartment | |
| pH | ~7.4 |
| Volume | 115 mL |
| Secretions | Sodium bicarbonate solution (as required) |
| Ileal compartment | |
| pH | ~7.4 |
| Volume | 115 mL |
| Secretions | Sodium bicarbonate solution (as required) |
| Time of half emptying | T1/2 = 220 min |
| β coefficient | 2.5 |