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. 2021 Apr 16;15:625490. doi: 10.3389/fnins.2021.625490

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Copyright © 2021 Harricharan, McKinnon and Lanius.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sensory transmission in PTSD + DS. Decreased insula subregion connectivity with the prefrontal cortex among individuals with the PTSD dissociative subtype (PTSD + DS) suggests a decreased capacity to relay incoming sensory information for multisensory integration. Instead, the PTSD dissociative subtype may translate sensory information from the insula to the occipital cortex, which is involved in implicit memory and visual imagery. PTSD + DS (PTSD Dissociative Subtype), SC/PAG (Superior Colliculus/Periaqueductal Gray), VN (Vestibular Nuclei), LC (Locus Coeruleus), Post Ins (Posterior Insula), Ant Ins (Anterior Insula), dlPFC (Dorsolateral Prefrontal Cortex).