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. 2021 Apr 16;11:665759. doi: 10.3389/fcimb.2021.665759

Table 1.

Recent efforts in the design of drug delivery methods for anti-pseudomonal therapies.

Chemical nature Avr. Particle size (nm) Cell type Effect  
Anionic liposome 100 Planktonic No difference between capsulated and free abx Wang et al., 2018
100 Biofilm Enhanced biofilm eradication Zahra et al., 2017
625 - 806.6 Planktonic and biofilm Prevents biofilm formation Alhariri et al., 2017
Graphene-oxide conjugates N/A Biofilm Enhanced biofilm eradication Dai et al., 2018
Poly(lactic-co-glycolic) acid nanoparticles 229.4 - 469.2 Planktonic No difference between capsulated and free abx Hill et al., 2019
132 - 348 Planktonic and biofilm Prevents biofilm formation Shaaban et al., 2017
Solid lipid nanoparticles 200 - 500 Planktonic No difference between capsulated and free abx Severino et al., 2017
Water-soluble chitosan oligosaccharide conjugates N/A Biofilm Enhanced biofilm eradication Li et al., 2019