Table 4.

Univariate and multivariate COX analysis for clinical factors.

Factors	Univariate COX analysis			Multivariate COX analysis
	HR	95%CI	P value	HR	95%CI	P value
Age	1.008	0.999–1.016	0.0560	1.012	1.004–1.021	0.0046
Sex (Female vs male)	1.074	0.880–1.309	0.4839	0.9519	0.778–1.165	0.6328
T stage (T3–4 vs T1–2)	2.541	1.851–3.489	<0.0001	1.964	1.425–2.705	<0.0001
N stage (N1–2 vs N0)	3.764	3.011–4.705	<0.0001	3.155	2.512–3.963	<0.0001
M stage (M1 vs M0)	4.781	2.974–7.688	<0.0001	3.070	1.887–4.994	<0.0001
Prognostic model	1.053	1.044–1.062	<0.0001	1.045	1.035–1.055	<0.0001