Table 5.
Univariate and multivariate analyses of overall survival in the training cohort.
| Characteristics | Univariate analysis | Multivariate analysis (step) | ||
|---|---|---|---|---|
| HR [95%CI] | P-value | HR [95%CI] | P-value | |
| AGE | ||||
| >50 years | Reference | Reference | ||
| ≤50 years | 0.98 [0.97, 0.99] | 0.003 | 1.56 [0.91, 2.69] | 0.106 |
| PRMARY ORGAN | ||||
| Bladder | Reference | |||
| Kidney | 0.71 [0.36, 1.38] | 0.308 | − | − |
| Other | 1.10 [0.47, 2.54] | 0.831 | − | − |
| Paratesticular | 0.70 [0.35, 1.40] | 0.319 | − | − |
| Prostate | 0.93 [0.41, 2.10] | 0.862 | − | − |
| GENDER | ||||
| Female | Reference | Reference | ||
| Male | 0.55 [0.32, 0.95] | 0.031 | 0.51 [0.30, 0.89] | 0.018 |
| SYMPTOM AT PRESENTATION | ||||
| No | Reference | |||
| Yes | 0.78 [0.32, 1.90] | 0.585 | − | − |
| SYMPTOM DURATION | ||||
| >1month | Reference | |||
| ≤1month | 1.00 [0.97, 1.05] | 0.822 | − | − |
| TUMOR SIZE | ||||
| >5cm | Reference | |||
| ≤5cm | 1.04 [0.99, 1.09] | 0.096 | − | − |
| HISTOLOGICAL SUBTYPE | ||||
| Liposarcoma | Reference | Reference | ||
| Leiomyosarcoma | 0.67 [0.39, 1.15] | 0.148 | 0.71 [0.37, 1.35] | 0.294 |
| Other | 0.75 [0.40, 1.38] | 0.350 | 0.59 [0.27, 1.29] | 0.185 |
| Rhabdomyosarcoma | 1.36 [0.72, 2.57] | 0.336 | 1.73 [0.78, 3.85] | 0.179 |
| METASTASIS_AT_ENTRY | ||||
| No | Reference | |||
| Yes | 1.00 [0.64, 1.57] | 0.990 | − | − |
| GRADE | ||||
| High | Reference | |||
| Low | 0.81 [0.46, 1.42] | 0.460 | − | − |
| SURGERY STATUS | ||||
| Surgery and margin negative | Reference | Reference | ||
| No surgery | 36.60 [17.27, 77.57] | <0.001 | 33.04 [14.37, 75.94] | <0.001 |
| Surgery and margin positive | 5.20 [2.76, 9.78] | <0.001 | 3.33 [1.70, 6.51] | <0.001 |
| CHEMOTHERAPY | ||||
| No | Reference | Reference | ||
| Yes | 0.47 [0.30, 0.75] | 0.002 | 0.56 [0.33, 0.95] | 0.030 |
| RADIOTHERAPY | ||||
| No | Reference | |||
| Yes | 0.94 [0.60, 1.48] | 0.792 | − | − |
Other in Primary organ included four genitourinary sites: ureter, seminal vesicles, and urethra. Other in histological subtype included Ewing′s sarcoma, primitive neuroectodermal tumor, synovial sarcoma, angiosarcoma, fibrosarcoma, malignant peripheral sheath tumor, myo-fibroblastic tumor, osteosarcoma, chondrosarcoma, and undifferentiated sarcoma.