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Histopathological grading of acute GvHD
| I. Vacuolar change at dermoepidermal junction |
| II. Changes in grade I, dyskeratotic cells, lymphocytic infiltration in dermis. |
| III. Changes in grade II, merging of the basal vacuoles and microvesicle formation |
| IV. Severe necrosis and denudation of epidermis, dermo-epidermal splitting. |
