Table 2.
Factors associated with bronchiolar telomere length (n = 120).
| Univariable | β (95% CI) | p |
|---|---|---|
| Donor age (per 10 years) | -0.095 (-0.137- -0.053) | <0.001 |
| Smoking history (per 10 pack years) | -0.067 (-0.122 - -0.012) | 0.017 |
| Time post-transplant (per 5 years) | 0.030 (-0.074 - 0.135) | 0.573 |
| CMV mismatch | -0.073 (-0.234 – 0.870) | 0.369 |
| Ischaemic time (per hour) | 0.007 (-0.0017 – 0.033) | 0.554 |
| Female sex | -0.033 (-0.156 – 0.090) | 0.598 |
| Pre-transplant diagnosis (compared to CF) COPD IPF other |
-0.121 (-0.268 – 0.026) -0.145 (-0.331 – 0.040) -0.097 (-0.302 – 0.107) |
0.107 0.125 0.350 |
| Donor female sex | -0.045 (-0.178 – 0.085) | 0.493 |
| PGD grade (24 hours) compared to PGD0 PGD1 PGD2 PGD3 |
-0.066 (-0.228 – 0.095) -0.051 (-0.241 – 0.139) -0.047 (-0.255 – 0.151) |
0.421 0.597 0.658 |
| Final independent variable | ||
| Donor age (per 10 years) | -0.095 (-0.137- -0.053) | <0.001 |