Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 15;12:645264. doi: 10.3389/fphar.2021.645264

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Boorgula, Jakkula, Gumbo, Jung and Srivastava.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Rifapentine kill curve and resistance emergence in the HFS-MAC. (A-C). There was no difference in the total as well as drug resistant subpopulation among the three rifapentine exposures tested in the HFS-MAC. The rifapentine monotherapy failed after 4 days of treatment. (D). Inhibitory Sigmoid E_max model showed highest r ² = 0.993 and lowest Akaike Information Criteria score (Akaike, 1974) = 0.080 on study day 4, where EC₅₀ was calculated as AUC/MIC of 1.025.