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Rifampin pharmacokinetics/pharmacodynamics indices for microbial kill in the HFS-MAC.
| Study day | Econ log10 CFU/mL | Emax log10 CFU/mL | EC50 fAUC/MIC | r 2 | |||
|---|---|---|---|---|---|---|---|
| Estimate | Standard error | Estimate | Standard error | Estimate | Standard error | ||
| 4 | 7.89 | 0.13 | 2.07 | 0.19 | 6.65 | 20.64 | 0.99 |
| 7 | 8.20 | 0.29 | 2.69 | 0.50 | 154.66 | 110.15 | 0.98 |
| 10 | 8.12 | 0.41 | 2.23 | 0.88 | 294.18 | 390.79 | 0.92 |
| 14 | 8.33 | 0.02 | 1.32 | 0.03 | 197.34 | 16.58 | 1.00 |
| 21 | 9.11 | 0.10 | 1.26 | 0.14 | 0.00 | 74.35 | 0.99 |
| 26 | 9.92 | 0.84 | 1.46 | 1.16 | 0.00 | 173.21 | 0.70 |
