TABLE 5.

Rifabutin pharmacokinetics/pharmacodynamics indices for microbial kill in the HFS-MAC.

Study day	Econ log10 CFU/mL		Emax log10 CFU/mL		EC50 fAUC/MIC		r 2
	Estimate	Standard error	Estimate	Standard error	Estimate	Standard error
4	7.88	0.37	1.68	0.58	0.00	171.80	0.94
7	8.20	0.26	2.41	0.47	118.38	141.94	0.97
10	8.06	0.50	4.29	8.25	2318.36	7350.63	0.86
14	8.33	0.15	1.21	0.26	50.39	125.52	0.97
21	9.11	0.27	1.30	0.46	50.32	209.32	0.93
26	9.93	0.98	0.83	1.53	0.00	904.01	0.38