Table 4. Person-Level Outcome Results for All Patients and Patients With vs Without Penicillin Allergies.
| Outcomes | All patients | Patients receiving parenteral treatment |
|---|---|---|
| All-cause mortality | ||
| Crude RRRR | 1.02 | NA |
| RRRRs from Poisson regression model (95% CI)a | 1.03 (0.94-1.13) | NA |
| Overall rate for patients with vs without penicillin allergy (95% CI) | 1.03 (1.01-1.06) | NA |
| Hospital days | ||
| Crude RRRR | 1.04 | 1.05 |
| RRRR from Poisson regression model (95% CI) | 1.04 (0.99-1.10) | 1.05 (0.99-1.11) |
| Overall rate for patients with vs without penicillin allergy (95% CI) | 1.09 (1.08-1.11) | 1.12 (1.10-1.14) |
| New Clostridioides difficile infection | ||
| Crude RRRR | 1.02 | 1.01 |
| RRRR from Poisson regression model (95% CI) | 1.02 (0.84-1.22) | 1.02 (0.82-1.26) |
| Overall rate for patients with vs without penicillin allergy (95% CI) | 1.23 (1.17-1.29) | 1.17 (1.11-1.24) |
| New MRSA infection | ||
| Crude RRRR | 0.87 | 0.88 |
| RRRR from Poisson regression model (95% CI) | 0.87 (0.75-1.00) | 0.88 (0.73-1.05) |
| Overall rate for patients with vs without penicillin allergy (95% CI) | 1.06 (1.02-1.10) | 1.14 (1.09-1.20) |
| New VRE infection | ||
| Crude RRRR | 0.82 | 0.77 |
| RRRR from Poisson regression model (95% CI) | 0.82 (0.55-1.22) | 0.78 (0.51-1.18) |
| Overall rate for patients with vs without penicillin allergy (95% CI) | 1.39 (1.26-1.53) | 1.38 (1.24-1.53) |
Abbreviations: MRSA, methicillin-resistant Staphylococcus aureus; NA, not applicable; RRRR, ratio of ratios of rate ratios; VRE, vancomycin-resistant Enterococcus.
a
Details are provided in the eMethods in the Supplement.