Table 3.
Characteristics | None (N = 19) | Rare (N = 85) | Frequent (N = 5) | P-value |
---|---|---|---|---|
Sex, N (%) | 0.0041 | |||
Female | 15 (79.0) | 36 (42.3) | 1 (20.0) | |
Male | 4 (21.0) | 49 (57.7) | 4 (80.0) | |
Age of Onset, Median (IQR) | 7.0 (4.0–10.5) | 7.5 (5.0–13.5) | 7.0 (5.0–9.0) | 0.4334 |
Duration of Illness (years), Median (IQR) | 4.6 (2.8–8.7) | 9.0 (5.8–12.5) | 18.3 (14.8–18.4) | 0.0005 |
Short GAA Repeat Length, Median (IQR) | 721.0 (550.0–900.0) | 700.0 (546.0–833.0) | 840.0 (771.0–850.0) | 0.3152 |
FARS Score, Median (IQR) | 52.5 (44.5–58.0) | 67.0 (46.7–78.0) | 100.0 (100.0–100.0) | 0.0656 |
Diminished Function, N (%) | 2 (14.3) | 4 (5.9) | 1 (33.3) | 0.0857 |
Hypertrophy, N (%) | 11 (84.6) | 50 (71.4) | 2 (66.7) | 0.5855 |
Patient and Disease characteristics by SVE Group. Abbreviation: FARS, Friedreich Ataxia Rating Scale; IQR, interquartile range