Table 1.
Presenting characteristics of 102 pediatric patients with acute osteomyelitis with and without abscess formation
| Variables | Bone abscess (n = 25) | Muscle abscess (n = 29) | Any abscess (n = 46) | No abscess (n = 56) | P-value for any vs. no abscess | |
|---|---|---|---|---|---|---|
| Demographic characteristicsa | Sex [n (%)] | |||||
| Male | 19 (76) | 23 (79) | 36 (78) | 39 (69) | 0.332 | |
| Female | 6 (24) | 6 (21) | 10 (22) | 17 (30) | ||
| Age [median (Q1, Q3)] (years) | 9.0 (3.0, 11.2) | 9.8 (5.8, 12.5) | 9.5 (4.4, 12.0) | 6.0 (2.0, 10.0) | 0.021 | |
| Ethnicity [n (%)] | ||||||
| White | 10 (40) | 11 (38) | 15 (33) | 11 (20) | 0.292 | |
| Hispanic | 10 (40) | 13 (45) | 21 (46) | 28 (50) | ||
| Native American | 4 (16) | 3 (10) | 7 (15) | 8 (14) | ||
| Other | 1 (4) | 2 (7) | 3 (7) | 9 (16) | ||
| Baseline clinical characteristicsb | Time to Presentation [median (Q1, Q3)] (days) | 7.0 (5.0, 11.0) | 7.0 (4.0, 13.0) | 6.5 (3.5, 12.0) | 5.0 (2.0, 14.0) | 0.261 |
| Admission WBC count [median (Q1, Q3)] (cells/ml) | 11.4 (9.4, 14.9) | 13.7 (10.0, 18.3) | 12.0 (9.5, 17.4) | 12.2 (8.8, 14.9) | 0.721 | |
| Admission CRP [median (Q1, Q3)] (mg/dl) | 17.3 (11.5, 24.2) | 12.3 (5.0, 24.1) | 13.5 (6.6, 25.3) | 5.1 (1.9, 9.4) | < 0.00011 | |
| Admission ESR (mm/h), Median (Q1, Q3) | 81.5 (56.0, 105.0) | 84.0 (39.5, 101.5) | 77.0 (38.0, 101.0) | 44.0 (18.0, 60.0) | 0.00051 | |
| Location of osteomyelitis [n (%)] | ||||||
| Femur | 7 (28) | 6 (21) | 10 (22) | 12 (21) | 0.972 | |
| Tibia/fibula | 11 (44) | 7 (24) | 15 (33) | 17 (30) | 0.812 | |
| Pelvis | 2 (8) | 6 (21) | 7 (15) | 7 (12) | 0.692 | |
| Ankle/foot | 5 (20) | 5 (17) | 8 (17) | 9 (16) | 0.862 | |
| Humerus | 3 (12) | 3 (10) | 6 (13) | 2 (4) | 0.082 | |
| Radius/ulna | 0 (0) | 1 (3) | 1 (2) | 1 (2) | 1.003 | |
| Other | 4 (16) | 6 (21) | 8 (17) | 11 (20) | 0.772 | |
| Multifocal osteomyelitis | 6 (24) | 11 (38) | 14 (30) | 6 (11) | 0.012 |
CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; WBC, white blood cell.
a
Compare P-values in this subset to Bonferroni-corrected type I error rate = 0.017.
b
Compare P-values in this subset to Bonferroni-corrected type I error rate = 0.0042.
1
P-value obtained from the Wilcoxon-rank sum test.
2
P-value obtained from the χ2-test.
3
P-value obtained from the Fisher exact test.