Table 2.
Correlation between EphA2 protein expression in breast cancer specimens and clinicopathologic factors
| Clinicopathologic factor | Expression of EphA2 protein | χ2 | p (n=250) | |
|---|---|---|---|---|
|
| ||||
| + (%) | - (%) | |||
| Age | ||||
| ≤45 years old | 72 (81.8) | 16 (18.2) | 3.549 | 0.060 |
| >45 years old | 115 (71.0) | 47 (29.0) | ||
| Tumor size | ||||
| <5 cm | 110 (71.9) | 43 (28.1) | 1.765 | 0.184 |
| ≥5 cm | 77 (79.4) | 20 (20.6) | ||
| Histologic type | ||||
| Invasive ductal carcinoma | 165 (76.4) | 51 (23.6) | 2.127 | 0.145 |
| Other types | 22 (64.7) | 12 (35.3) | ||
| TNM stage | ||||
| 0-l stage | 12 (48.0) | 13 (52.0) | 16.303 | 0.000 |
| ll stage | 84 (71.2) | 34 (28.8) | ||
| lll-lV stage | 91 (85.0) | 16 (15.0) | ||
| Lymphatic metastasis | ||||
| + | 137 (84.6) | 25 (15.4) | 23.296 | 0.000 |
| - | 50 (56.8) | 38 (43.2) | ||
| Histologic grade | ||||
| l | 18 (54.5) | 15 (45.5) | 9.119 | 0.010 |
| ll | 118 (79.7) | 30 (20.3) | ||
| lll | 51 (73.9) | 18 (26.1) | ||