Overexpressing p21 partially counteracts the anti-migration/invasion effect of LH. A, B. Migration and invasion of p21/vector-overexpressing cells under LH (20 μM) or DMSO treatment. Scale bar, 100 μm. C, D. p21, E-cadherin, N-cadherin, and Vimentin proteins in p21/vector-overexpressing cells after LH (20 μM) or DMSO treatment for 48 h. Mean ± SD; **P<0.01, ***P<0.001.