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. 2021 Apr 15;11(4):1428–1445.

Figure 6.

Figure 6

Loss of IGF2BP3 enhanced the response of HCT8/T xenografts to NVB and PTX. NVB or PTX were intraperitoneally administered to nude mice bearing xenografts derived from IGF2BP3-knockdown or control HCT8/T cells for 20 days. A-C. Changes in relative tumor volume (RTV), tumor weight and body weight along the days of inoculation. D. Images of the xenografts at the end of treatments. E. Western blotting analysis showing the expression of ABCB1 and IGF2BP3 proteins in xenograft tumors. Densitometry analysis of protein bands was performed using Image J. *, P <0.05; **, P <0.01, ***, P < 0.001 (Student’s t-test).