Table 5.
Correlation among ABCB1 expression, DOX sensitivity and IGF2BP3 expression in CRC lines
| CRC cell lines | Relative expression of IGF2BP3 | Relative expression of ABCB1 | DOX |
|---|---|---|---|
|
| |||
| IC50 (mean ± SD) (μM) | |||
| SW620 | 1.9557±0.4754 | 10.4842±1.5194 | 0.3397±0.0335 |
| DLD1 | 1.3759±0.2247 | 8.8091±1.1620 | 0.2195±0.0354 |
| HT29 | 1.8044±0.1104 | 5.9175±1.1977 | 0.1669±0.0079 |
| HCT15 | 1.6345±0.3697 | 4.0163±0.8954 | 0.1515±0.0411 |
| HCT8 | 1.1126±0.1827 | 3.4658±0.7837 | 0.1071±0.0032 |
| SW480 | 0.7210±0.0952 | 1.3822±0.3628 | 0.0482±0.0070 |
| SW1463 | 0.4431±0.1431 | 2.0618±0.3937 | 0.0252±0.0058 |
| HCT116 | 1.0000±0.1015 | 1.0000±0.1039 | 0.0119±0.0010 |
The experiments were conducted as described in Materials and methods. Data are shown as mean ± SD (n = 3).