FIGURE 1.

Self‐reported craving, psychological distress, and health and well‐being after lorcaserin treatment in participants with alcohol use disorder (AUD) and methamphetamine use disorder (MUD). Total obsessive compulsive drinking score over the 28‐day treatment period. Total n = 8. **p < .01 for each craving measure (A). Average craving score over the 28‐day treatment period. n = 3–5. *p < .05 baseline to Day 14 (B). Kessler Psychological Distress self‐report data over the 28‐day treatment period. Total n = 8 for AUD participants, n = 3–5 for MUD participants. ***p < .001 (C and D). Psychological health status and quality of life increased over the treatment period; however, there was no significant change in physical health status for AUD participants. Total n = 8. **p < .01 for psychological health status and quality of life (E). Psychological health status increased over the treatment period; however, there was no significant change in physical health status or quality of life. n = 2–5. ***p = 0.001 for psychological health status (F). All data are presented as mean ± SEM