TABLE 4.
Associations Between SES and Demographics and Clinical Outcomes in Patients With MIS-C
| Neighborhood SES Summary Scorea | SVIb | |||||
|---|---|---|---|---|---|---|
| Lowest Quartile (n = 22) | Top 3 Quartiles (n = 21) | P | Highest Quartile (n = 23) | Bottom 3 Quartiles (n = 20) | P | |
| Demographics | ||||||
| Age, y, median (IQR) | 9.6 (6.3 to 13.3) | 10.3 (7.0 to 16.6) | .58 | 9.7 (6.5 to 14.9) | 9.3 (6.3 to 16.6) | .88 |
| Male sex, n (%) | 13 (61) | 12 (57) | .99 | 14 (61) | 11 (55) | .76 |
| Weight, kg, median (IQR) | 44.1 (27.2 to 61.7) | 36.0 (22.7 to 726.3) | .58 | 45.1 (28.5 to 74.1) | 33.7 (21.6 to 72.5) | .53 |
| BMI, median (IQR) | 21.3 (18.4 to 26.2) | 22.3 (16.7 to 27.6) | .95 | 24.2 (18.6 to 29.8) | 19.9 (16.5 to 25.2) | .10 |
| Comorbidities, n (%) | 11 (50) | 8 (38) | .54 | 11 (48) | 8 (40) | .76 |
| Obesity, n (%) | 8 (36) | 9 (43) | .76 | 10 (43) | 7 (35) | .76 |
| Hospital course | ||||||
| Days of fever, median (IQR) | 6.0 (4.0 to 7.8) | 7.0 (5.0 to 7.0) | .52 | 7.0 (4.5 to 7.5) | 6.5 (5.0 to 7.3) | .94 |
| Hospital LOS, d, median (IQR) | 6.5 (4.0 to 9.8) | 6.0 (3.0 to 10.0) | .78 | 6.0 (4.0 to 9.5) | 5.5 (3.0 to 10.5) | .67 |
| ICU admission, n (%) | 11 (50) | 8 (38) | .54 | 12 (52) | 7 (35) | .36 |
| ICU LOS, d, median (IQR) | 4.5 (2.0 to 6.6) | 4.0 (3.0 to 7.0) | .77 | 4.5 (2.0 to 7.0) | 4.0 (3.0 to 8.0) | .56 |
| Inotropes, n (%) | 4 (18) | 4 (19) | .99 | 4 (17) | 4 (20) | .99 |
| PPV, n (%) | 3 (14) | 2 (10) | .99 | 2 (9) | 3 (15) | .65 |
| Intubation, n (%) | 2 (9) | 2 (10) | .99 | 3 (13) | 1 (5) | .61 |
| Cardiac involvement, n (%) | ||||||
| Elevated BNP level | 15 (68) | 10 (48) | .33 | 14 (61) | 11 (55) | .75 |
| Elevated troponin level | 5 (23) | 8 (38) | .733 | 6 (26) | 7 (35) | .74 |
| Ventricular dysfunction | 9 (41) | 12 (57) | .37 | 10 (43) | 11 (55) | .55 |
| Coronary artery dilation | 8 (36) | 2 (10) | .07 | 8 (35) | 2 (10) | .08 |
| Atrioventricular block | 2 (9) | 2 (10) | .99 | 2 (9) | 2 (10) | .99 |
| Treatment, n (%) | ||||||
| IVIg | 17 (77) | 17 (81) | .99 | 19 (83) | 15 (75) | .71 |
| Steroids | 16 (73) | 14 (67) | .74 | 17 (74) | 13 (65) | .74 |
| Anakinra | 6 (27) | 3 (14) | .46 | 5 (22) | 4 (20) | .99 |
BNP, brain natriuretic peptide; IVIg, intravenous immunoglobulin; LOS, length of stay; PPV, positive pressure ventilation.
a
Neighborhood summary scores are reported as z scores.
b
SVI is a percentage, with higher percentages denoting increased vulnerability.