TABLE 3.
Age, mo | ||||||
---|---|---|---|---|---|---|
6 | 12 | 18 | 24 | 30 | 36 | |
ELC, mean (SD) | ||||||
Girl with a premutation | −7.60 (1.06) | −6.20 (0.93) | −4.39 (0.88) | −4.54 (0.96) | −3.98 (1.04) | −1.50 (1.17) |
Boy with a premutation | −3.17 (1.34) | −3.10 (1.21) | −2.47 (1.23) | −3.42 (1.25) | −3.86 (1.31) | −2.24 (1.47) |
Girl with an FM | −10.76 (0.84) | −13.74 (0.74) | −16.59 (0.71)a | −18.82 (0.72)a | −20.96 (0.68)a | −23.00 (0.69)a |
Boy with an FM | −29.27 (0.59)a | −32.01 (0.53)b | −35.17 (0.49)b | −37.39 (0.49)b | −39.67 (0.44)b | −43.01 (0.41)b |
Gross motor | ||||||
Girl with a premutation | −3.71 (1.00) | −2.72 (0.72) | −1.73 (0.70) | −0.74 (0.95) | 0.25 (1.33) | — |
Boy with a premutation | −4.49 (1.58) | −3.21 (1.07) | −1.94 (1.25) | −0.66 (1.93) | 0.62 (2.77) | — |
Girl with an FM | −9.10 (0.82) | −9.51 (0.59)a | −9.92 (0.54)a | −10.34 (0.70)a | −10.75 (0.98)a | — |
Boy with an FM | −15.10 (0.61)a | −17.61 (0.44)a | −20.12 (0.35)b | −22.63 (0.40)b | −25.14 (0.56)b | — |
Visual receptive, mean (SD) | ||||||
Girl with a premutation | −1.90 (0.82) | −1.29 (0.71) | −0.60 (0.66) | −1.01 (0.70) | −0.93 (0.76) | 0.06 (0.87) |
Boy with a premutation | −1.03 (1.04) | −1.05 (0.92) | −0.72 (0.90) | −1.61 (0.90) | −2.13 (0.94) | −1.42 (1.07) |
Girl with an FM | −4.03 (0.65) | −5.24 (0.57) | −6.57 (0.53) | −7.97 (0.52) | −9.16 (0.49) | −10.33 (0.51)a |
Boy with an FM | −14.49 (0.46)a | −16.18 (0.40)a | −18.11 (0.36)a | −19.82 (0.36)b | −21.46 (0.32)b | −23.66 (0.30)b |
Fine motor, mean (SD) | ||||||
Girl with a premutation | −1.42 (0.91) | −1.15 (0.84) | −1.45 (0.72) | −1.75 (0.68) | −0.36 (0.70) | −0.90 (0.80) |
Boy with a premutation | −3.96 (1.14) | −3.86 (1.08) | −4.25 (0.93) | −4.64 (0.87) | −3.41 (0.92) | −4.32 (1.00) |
Girl with an FM | −3.65 (0.71) | −6.70 (0.68) | −8.79 (0.58) | −10.88 (0.51)a | −13.23 (0.47)a | −15.38 (0.48)a |
Boy with an FM | −15.24 (0.50)a | −17.99 (0.48)a | −19.76 (0.41)b | −21.54 (0.35)b | −24.47 (0.29)b | −26.20 (0.28)b |
Receptive language, mean (SD) | ||||||
Girl with a premutation | −4.78 (0.81) | −4.00 (0.70) | −3.10 (0.65) | −2.85 (0.69) | −2.41 (0.75) | −1.29 (0.86) |
Boy with a premutation | −0.12 (1.02) | −0.51 (0.91) | −0.49 (0.90) | −0.46 (0.90) | −0.70 (0.95) | −0.04 (1.08) |
Girl with an FM | −7.58 (0.64) | −9.14 (0.56) | −10.41 (0.52)a | −11.17 (0.52)a | −12.02 (0.49)a | −12.69 (0.50)a |
Boy with an FM | −16.12 (0.45)a | −17.76 (0.40)a | −19.43 (0.36)a | −20.59 (0.36)b | −21.90 (0.32)b | −23.62 (0.30)b |
Expressive language, mean (SD) | ||||||
Girl with a premutation | −7.43 (0.72) | −6.30 (0.62) | −5.04 (0.58) | −4.42 (0.62) | −3.65 (0.67) | −2.00 (0.76) |
Boy with a premutation | −1.70 (0.91) | −1.46 (0.81) | −1.37 (0.79) | −1.76 (0.80) | −1.91 (0.84) | −1.05 (0.95) |
Girl with an FM | −8.69 (0.57) | −9.99 (0.50)a | −11.19 (0.46)a | −11.84 (0.47)a | −12.63 (0.44)a | −13.30 (0.45)a |
Boy with an FM | −18.61 (0.40)a | −19.88 (0.35)b | −21.34 (0.32)b | −22.36 (0.32)b | −23.45 (0.28)b | −25.03 (0.27)b |
ELC has mean of 100 and SD of 15. t score has mean of 50 and SD of 10. FM, full mutation; —, not applicable.
t score <1 SD from mean.
t score <2 SD from mean.