Table 2.
Radiobiological Parameters
| Cell lines | N (Mean ± SDa) | D0 (Mean ± SDa) | Dq (Mean ± SDa) | SF2 (Mean ± SDa) |
|---|---|---|---|---|
| MCF-7-vector | 3.06 ± 0.28 | 1.00 ± 0.05 | 1.12 ± 0.13 | 0.36 ± 0.05 |
| MCF-7-ALG3 | 4.90 ± 0.82 | 1.42 ± 0.12 | 2.24 ± 0.05 | 0.74 ± 0.02 |
| ZR-75-30-vector | 2.04 ± 0.35 | 1.09 ± 0.09 | 0.76 ± 0.17 | 0.30 ± 0.04 |
| ZR-75-30-ALG3 | 4.96 ± 1.22 | 1.40 ± 0.14 | 2.20 ± 0.14 | 0.73 ± 0.03 |
| MDA-MB-231-control | 5.48 ± 1.92 | 1.52 ± 0.14 | 2.50 ± 0.34 | 0.81 ± 0.08 |
| MDA-MB-231-sg1 | 2.10 ± 0.17 | 1.20 ± 0.17 | 0.90 ± 0.15 | 0.36 ± 0.09 |
| MDA-MB-231-sg2 | 1.63 ± 0.70 | 1.21 ± 0.08 | 0.50 ± 0.43 | 0.28 ± 0.07 |
| SUM159PT-control | 3.98 ± 0.44 | 1.52 ± 0.03 | 2.10 ± 0.13 | 0.71 ± 0.03 |
| SUM159PT-sg1 | 1.59 ± 0.40 | 1.26 ± 0.06 | 0.55 ± 0.35 | 0.30 ± 0.06 |
| SUM159PT-sg2 | 2.28 ± 0.09 | 1.17 ± 0.12 | 0.95 ± 0.15 | 0.36 ± 0.04 |
N extrapolation number, D0 mean lethal dose, Dq quasi-threshold Dose, SF2 surviving fraction at 2 Gy
aMean ± SD represents mean values of surviving fractions ± standard deviations