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. 2021 Apr 30;40:149. doi: 10.1186/s13046-021-01932-8

Table 4.

Association between ALG3 expression and other clinicopathologic

Features of breast cancer No. of patients ALG3 expression p values
Low expression High expression
Age 0.920
  ≤ 50 225 121 104
  > 50 151 82 69
Stage (AJCC) 0.010#
 I ~ II 188 114 74
 III ~ IV 188 89 99
T 0.017#
 T1 ~ T2 290 164 126
 T3 ~ T4 86 39 47
N 0.028#
 N0 ~ N2 205 123 82
 N2 ~ N3 171 80 91
Histological grade 0.068#
 1 108 69 39
 2 179 88 91
 3 89 46 43
ER 0.011
 Negative 169 79 90
 Positive 207 124 83
 Missing 0
PR 0.049
 Negative 124 58 66
 Positive 252 145 107
 Missing 0
HER2 0.205
 Negative 211 158 124
 Positive 165 45 49
 Missing 0
Ki67 0.001#
 Low expressiona 281 161 120
 High expressionb 88 42 46
 Missing 7
Mutational p53 0.001#
 Low expressiona 196 133 90
 High expressionb 165 64 74
 Missing 15
VEGF 0.167#
 Low expressiona 302 165 147
 High expressionb 64 38 26
 Missing 10

p -values and #p -values were calculated with the chi-square test and continuity correlation, respectively

aLow expression represented -, +, ++ staining index in IHC examination

bHigh expression represented +++, ++++ staining index in IHC examination