Table 5.

Univariate analyses of prognostic factors in breast cancer using a Cox regression model

		Univariate analyses (OS)		Univariate analyses (LRFS)
	No. of patients	p	EXP(B) (SE)	p	EXP(B) (SE)
ALG3		< 0.001	2.702 (0.180)	0.013	1.739 (0.147)
Low expression	203
High expression	173
Age		0.339	1.181 (1.174)	0.350	0.8698 (0.151)
≤ 50	225
> 50	151
Stage (AJCC)		< 0.001	1.851 (0.176)	0.352	1.146 (0.146)
I ~ II	188
III	188
T		0.098	1.384 (0.196)	0.620	1.091 (0.175)
T1 ~ T2	290
T3 ~ T4	86
N		< 0.001	1.991 (0.174)	0.022	1.397 (0.146)
N0 ~ N2	205
N2 ~ N3	171
Histological grade
1(indicator)	108
2	179	0.021	1.644 (0.216)	0.065	0.917 (0.167)
3	89	< 0.001	3.301 (0.247)	0.047	1.483 (0.198)
ER		< 0.001	0.444 (0.1745)	< 0.001	0.445 (0.148)
Negative	169
Positive	207
Missing	0
PR		< 0.001	0.496 (0.174)	< 0.001	0.430 (0.147)
Negative	124
Positive	252
Missing	0
HER2		0.008	1.582 (0.172)	< 0.001	1.729 (0.147)
Negative	211
Positive	165
Missing	0
Ki67		< 0.001	2.006 (0.180)	< 0.001	3.547 (0.149)
Low expressiona	281
High expressionb	88
Missing	7
Mutational P53		< 0.001	2.139 (0.177)	< 0.001	2.695 (0.150)
Low expressiona	196
High expressionb	165
Missing	15
VEGF		0.853	1.042 (0.222)	0.128	1.315 (0.180)
Low expressiona	302
High expressionb	64
Missing	10

^aLow expression represented -, +, ++ staining index in IHC examination

^bHigh expression represented +++, ++++ staining index in IHC examination