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Quantification of peptide and protein stability (reported as fraction of intact molecule) following incubation in 25% (v/v) human AB serum for 0 to 48 h. Fractions of intact S1H were determined from analytical HPLC chromatograms; fractions of intact hGH and pegvisomant (Peg.) were determined using western blots. See Experimental procedures and supporting information for experimental details. hGH, human growth hormone.
