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. 2021 Mar 23;3(1):vdab046. doi: 10.1093/noajnl/vdab046

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© The Author(s) 2021. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — GPR133 is de novo expressed in GBM. Representative micrographs of GPR133 immunohistochemistry⁷⁸ from the subependymal zone of non-neoplastic cadaveric brain (A) and an IDH wild-type GBM (B). The subependymal zone around the brain ventricular system contains progenitor cells that may represent the putative cell of origin for glioma.