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. 2021 Apr 29;16:36. doi: 10.1186/s13020-021-00444-z

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 10 — Photomicrographs of hematoxylin and eosin stained sections of the liver in the different treated groups (×400). a Negative control group showing normal hepatic architecture, b PCOS group showing moderate vacuolation of hepatocytes. c Clomiphene treated group showing mild vacuolation of hepatocytes. d Actaea racemose (AR) treated group showing hepatocellular necrosis with sinusoidal dilation and disorganization of hepatic cords. e Vitamin C group showing normal histological findings. f AR combined with vitamin C group showing mild vacuolation of hepatocytes with sporadic cell necrosis