Fig. 3.

Effects of novel environment on colonic (A) or locomotor (B) responses in male CRF-OE mice and WT littermates. Time course analysis shows enhanced colonic response during the first 15 min in both CRF-OE mice and WT littermates (A) and decreased locomotor response during the 45–60 min (B) of the stress session monitored concomitantly. Each bar or point represents the mean ± SE of number of mice indicated in parentheses. *P < 0.05 vs. all other time points (repeated one-way ANOVA); #P < 0.05 vs. WT littermates at 45–60 min time point (t-test).