Figure 1:

In hematopoiesis, leptin significantly stimulates the appearance of granulocyte-macrophage colonies (CFU-GM), the precursor for monocytes and granulocytes. CFU-EO = colony forming uniteosinophils; CFU-GM = colony forming unit-granulocyte, macrophage; CFU-MEG = colony forming unitmegakaryocyte; BFU-E, burst-forming unit-erythroid; LepR = leptin receptor. All figures were created with BioRender.com