FIGURE 1.

Wnts promote inhibitory phosphorylation of Gsk3β at Ser9 in the cochlea. (A–L) pS9-Gsk3β (green), acetylated-tubulin (red), and phalloidin (blue) staining at the level of the hair bundle in control (A–F) and Wls^cKO (G–L) OC at E18.5. Open arrowheads indicate the pericentriolar region. Arrowheads indicate the tip of the kinocilium. (M–P) pS9-Gsk3β and phalloidin staining at the level of adherens junctions in control (M,N) and Wls^cKO (O,P) OC and surrounding regions. Brackets indicate the OC. Lateral is up. Scale bars: (A–L), 6 μm; (M–P), 10 μm.