Table 6.

Comparison of serum coenzyme Q₁₀ (CoQ₁₀) and overall event rates and risk reduction at 2 years in the European and total population.

Endpoint	European sub-population				Total population
	CoQ10 (n = 108)	Placebo (n = 123)	RRR	P	CoQ10 (n = 202)	Placebo (n = 218)	RRR	P
CoQ10-S [μg/mL]	3.55	0.76		< 0.001	2.01	0.81		< 0.001
MACE	9%	27%	66%	0.001	15%	26%	43%	0.005
Death from any cause	9%	20%	53%	0.040	10%	18%	42%	0.036
Cardiovascular death	8%	17%	51%	0.052	9%	16%	43%	0.039
Hospitalization for HF	3%	13%	79%	0.007	8%	14%	41%	0.067

HF — heart failure; MACE — major adverse cardiovascular events; RRR — relative risk reduction